In many structural components such as beams, columns or plates, failure develops not only from excessive stresses but also from buckling. The buckling behavior of plates subjected to in-plane loads is an important aspect in the preliminary design of any structural component. The knowledge of critical buckling loads, mode shapes is vital for reliable structural design. There is a necessity for providing the holes of various shapes in the plates for various purposes. In this paper, the buckling behavior of rectangular plates with holes of various shapes is investigated. The finite element modeling and buckling analysis of the plates has been carried out using ANSYS 14.5. Plates with three varieties of shapes of holes i.e., Triangular, Square and Rhombus have been studied. The plates are investigated for different positions of the holes (i.e. Center, Top) and for various a/b ratios ranging from 2 to 12 at an increment of 2 and for various b/t ratios ranging from 20 to 100 at an increment of 20. Finally, buckling loads of the plates with holes is compared wrt. shape of the hole, location of the hole and some useful conclusions are drawn.