Castleman Disease of Hyaline Vascular Type: The Ignored Lymphoproliferative Condition

Ramzana Abdul Rasheed*, Aneeta Toms**
*-** Department of Pharmacy Practice, The Dale View College of Pharmacy and Research Centre (Autonomous), Thiruvananthapuram.
Periodicity:July - December'2025
DOI : https://doi.org/10.26634/djcp.2.2.22372

Abstract

Hyaline vascular type Castleman disease (HV-CD) is a rare but distinct benign lymphoproliferative disorder that is a subtype of unicentric Castleman disease (UCD). Its lack of symptoms, unusual histopathological patterns, and localized appearance frequently make it hard to tell apart from lymphomas or other reactive lymphadenopathies. To avoid overtreatment, it is important to recognize and correctly differentiate quickly, since complete surgical excision is typically curative. Castleman disease (CD) is a rare, non-clonal lymphoproliferative disorder that shows up as a group of different types of lymph node growths. The hyaline vascular type (HV-CD) is the most common histological variant found in unicentric CD (UCD). It usually has a benign, asymptomatic course.

Keywords

Castleman Disease, Unicentric Lymphadenopathy, Lollipop Lesion, Onion Peeling, Lymphoid Hyperplasia, Angiogenesis.

How to Cite this Article?

Rasheed, R., and Toms, A. (2025). Castleman Disease of Hyaline Vascular Type: The Ignored Lymphoproliferative Condition. Dale View's Journal of Clinical Pharmacology and Pharmacotherapeutics, 2(2), 22-32. https://doi.org/10.26634/djcp.2.2.22372

References

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