Women entrepreneurs are woman or a group of women who run a business enterprise on their own. The various functions of women entrepreneurs include risk mitigation, creating new innovations, administering and managing the enterprise, and most importantly, maintaining work-life balance. India is clearly seeing a revolution as many women are entering the world of business with the aid of globalization, digitalization, and start-ups. All types of women with different backgrounds enter into business, unlike in those days, when women entrepreneurs came from established family business backgrounds or those belonging to higher income groups. A woman entrepreneur requires a positive quality and power in order to sustain herself in the industry in the long run. However, as per the sixth economic census released by the Ministry of Statistics and Programmed Implementation (MoSPI), only fourteen percent of the total entrepreneurship in India is women. Hence, it is proved that women owned firms are still low in India and one of the major reason is due to gender inequality. The objective of this study is to examine the role of women entrepreneurs in Kanyakumari District in overcoming socio-economic and cultural barriers to establish and grow their businesses. A structured questionnaire was framed, and 120 primary data were collected with the use of Google Forms through the convenience sampling method. The secondary data collection was through books, journals, and websites. The findings emphasize the need for empowering women through supportive measures to ensure their long-term success in the entrepreneurial ecosystem. The study underscores the resilience and transformative potential of women entrepreneurs in Kanyakumari District, serving as a testament to their determination to break barriers and contribute meaningfully to economic and social progress.