The proliferation of spam comments on platforms like YouTube poses a significant challenge, degrading user experience and potentially spreading malicious content or misinformation. This paper provides a comprehensive overview of developing a YouTube spam comment recognition system utilizing Python, Artificial Intelligence (AI), and Machine Learning (ML) techniques. It details the entire pipeline, from data acquisition and preprocessing of textual comment data to feature extraction methodologies suitable for text, selection and training of appropriate ML and AI models, and robust evaluation strategies. The paper also discusses key Python libraries and frameworks instrumental in implementing such systems, alongside an exploration of common challenges like evolving spam tactics and dataset imbalances, and outlines potential future research directions in this domain. The goal is to equip researchers and practitioners with a foundational understanding for building effective automated spam detection systems for online comment sections.