Adolescence is a vital stage of human development, characterized by significant physical, emotional, and cognitive changes. During this period, adolescents face numerous challenges, including academic stress, mental health issues, social pressures, and identity formation. Teachers play a significant role in shaping students' academic and personal growth, so their ability to provide guidance and support is essential. However, research suggests that many teachers lack the necessary training, resources, and institutional support to effectively address these challenges. This study aims to highlight the need for strengthening teachers' roles in supporting adolescent development through targeted training programs, collaborative approaches, and policy reforms. This study employs a systematic thematic analysis to examine existing literature on teacher preparedness in addressing adolescent challenges. Research indicates a growing prevalence of mental health concerns, such as anxiety and depression, exacerbated by academic stress and social media influence. Although teachers are often the first to notice behavioral changes in students, they frequently lack the expertise to provide appropriate interventions. Institutional constraints, including high workloads and limited resources, further hinder their ability to offer holistic support. This study underscores the importance of equipping teachers with adolescent psychology knowledge, mental health literacy, and trauma-informed teaching strategies by synthesizing research findings. It advocates for the integration of multidisciplinary support systems within schools, offering valuable insights for policymakers, teachers, and stakeholders in designing evidence-based interventions that enhance teacher effectiveness and promote student well-being.