Substance use is a pattern of harmful use of any substance for mood-altering purposes. Substance abuse can include alcohol, tobacco, illegal drugs, inhalants, solvents, nicotine, and prescription and over-the-counter drugs, etc. The conceptual framework used for the study was Callista Roy's adaptation model. The goal of the study is to prove that the relaxation programme is an effective intervention in addiction recovery and well-being among substance use adults. The study used a quasi-experimental pre-test, post-test, and control group research design. A purposive sampling technique was adopted. A total of 70 substance use adults (35 experimental group, 35 control group) fulfilled the inclusive criteria. Socio-demographic and clinical data, unstructured questionnaire for pre-test and post-test were administered in face to face method, after getting informed consent. The experimental group received a relaxation programme. The data were analyzed based on the objective and hypotheses of the study. The relaxation programme was effective in addiction recovery and improved well-being. There was a significant positive relationship between post- test addiction recovery and well-being scores among substance use adults. There will be a significant association between the pre-test level of addiction recovery and well-being in age, education, type of abuse, and onset of abuse. Thus, the study concluded that the relaxation programme is an effective intervention in addiction recovery and well- being among substance use adults.