A pandemic is an epidemic issue that spreads all over the world. COVID-19 started in December 2019 at Wuhan city in China. The common features of this virus are cold, flu, fever and sore throat with more severe lung involvement in a few samples for which different scientists are struggling to find a treatment. However, directly and indirectly, COVID has increased social stigma and challenges for the affected population, and health professionals, that has impact on their psychological health. The prevention of social stigma and negative psychological issue is very important at the individual and community level. Nurses are the ones who play an important role in preventing the social stigma by helping to overcome challenges.