Significant structural collapses happen when a structure is exposed to dynamic loads, such as wind and earthquake loads. The majority of contemporary buildings include architectural meaning, which makes regular form planning extremely challenging. When dynamic loads cause a building to collapse, these anomalies are to fault. It is recommended that all structural analyses be carried out using the ETABS software package to accurately obtain displacement values and other structural responses. This study examines Marcos 3-D of G+20 floors with asymmetric vertical configuration starting on the ninth level and symmetric lifting arrangement throughout its height. Determining the answers of every prior table for every possible combination of loads is suggested. The dynamic analysis is authorized by IS 1893 (Part 1): 2016 and the response spectrum analysis method is recommended to determine the lateral forces and shear demands on the floors of the three building models resulting from seismic loads. (Analysis of linear dynamics). Therefore, even with subpar configuration, considerable research is needed to attain optimal performance. The impacts of dough inconsistency and vertical irregularity under dynamic stresses in multi-story buildings are examined in this study. Three reinforced concrete (RC) building frames have been selected for the study, and it is recommended that each frame be individually modeled and analyzed in detail.