The paper presents need and importance of expanding horizons, visions and missions of leaders in universities and colleges to meet local and global challenges. Strategic visions and missions from the world ranking universities like Stanford and MIT are presented in this paper for adoption and implementation by Indian universities and colleges. Today leaders of Indian universities and colleges are found to limit their visions and missions largely to teaching and do not adequately reach to research, innovation and creativity. Organizational and management strategic visions of foreign universities which are relevant to Indian situation and can make a big difference in them are also presented. New knowledge and new technology generation in Indian universities is far too low. Technology transfer from university to human society is far too weak. Marketing of new knowledge and technology from university to human society is almost absent. NEP-2020 has very ably outlined the challenges before higher and technical education in India. Now it remains for Indian universities and colleges to implement them effectively. Government is very serious about implementation, because it is the key to people's development. Indian youths in 21st century need to be nurtured to face not only local but also global challenges. Effective implementation of NEP-2020 is however not an easy job. It essentially requires modern strategic visions on the part of university leaders, governing body members of universities and colleges. Every university and college must have to cope with global winds of change, welcome them and discuss, debate and adopt them with suitable modifications, if necessary. The purpose of the paper is to develop awareness among leaders in university and colleges about experiences from world ranking universities. Capability building of human resources takes place in universities and colleges which in turn increases ability of people to see and meet challenges at local and global levels. Projects like Atna Nirbhar Bharat, Skill India, Make in India etc will stand to gain if NEP-2020 is effectively implemented. If all the leaders in universities and colleges adopt the modern visions and missions then Indian education will shoot over the world and undoubtedly India will become a hub of education.