There has been a growing trend towards using hand piece driven rotary instrumentation techniques in dentistry. These instruments are designed to prepare teeth using crown-down technique, which reduces the amount of debris that is pushed down towards the apex. Recently, advanced instrument designs have been developed, which include non-cutting tips, radial lands, different cross sections, and varying tapers. These designs are aimed at improving working safety and shortening working time, and have been shown to produce less debris than traditional hand filing techniques. The purpose of this study was to evaluate the amount of debris and volume of irrigant extruded apically using three different rotary nickel titanium endodontic instruments: Profile, Protaper, and Race.